When the story is, "look what the FDA decided," you know it's a "please invest in our company" story. Of course, that's what I've come to expect from Business Wire, but there's a little info about the drug too.
Cyclosporin is a unique neuron-protecting drug, with the advantage that it is the only one in development that is a direct mitochondrial neuroprotectant. Cyclosporin targets the mitochondria for stabilization and preservation, blocking both the apoptotic and necrotic pathways that cause neuronal death. The mitochondria are "waterproofed" by cyclosporin and neurons are able to continue functioning under the conditions of attack seen in ALS.This is another "slowing onset and extending lifespan" drug.
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